Тable 3. Dynamics of cytokines in saliva depending on the size of the tumor
|
Indicator |
T1N0-3M0-1, n=9 |
T2N0-3M0-1, n=30 |
T3N0-3M0-1, n=21 |
T4N0-3M0-1, n=10 |
|
IL-2 |
2.61 [1.66; 4.94] |
1.11 [0.64; 2.13] p=0.0069 |
1.14 [0.81; 2.73] p=0.0404 |
1.02 [0.60; 2.52] p=0.0410 |
|
IL-4 |
1.47 [0.68; 2.00] |
1.00 [0.16; 1.66] |
0.53 [0.20; 1.05] p=0.0193 |
0.73 [0.35; 1.16] |
|
IL-6 |
0.86 [0.56; 3.93] |
0.75 [0.44; 2.34] |
1.18 [0.33; 1.81] |
4.17 [4.00; 4.33] |
|
IL-8 |
68.90 [54.40; 171.50] |
130.00 [66.58; 249.00] |
98.20 [51.70; 160.16] |
151.00 [117.00; 331.72] |
|
IL-10 |
2.71 [1.93; 13.10] |
2.01 [0.91; 2.65] p=0.0486 |
2.09 [1.29; 3.03] |
1.78 [1.33; 2.41] p=0.0485 |
|
IL-18 |
19.10 [9.68; 60.55] |
9.80 [4.28; 68.90] |
11.50 [4.59; 33.80] |
42.40 [13.60; 170.00] |
|
CRP |
0.017 [0.015; 0.020] |
0.024 [0.015; 0.041] |
0.033 [0.012; 0.121] |
0.044 [0.024; 0.056] p=0.0367 |
|
TNF-α |
No data |
No data |
0.88 [0.49; 1.71] |
1.26 [0.42; 1.90] |
Notes. p – statistically significant differences compared to the group T1N0-3M0-1