Table 2. Effect of blueberry leaves (Vaccinium myrtillus) extract on the survival of cultured neurons under the action of glutamate. The number of live neurons after incubation with the test substances after 18 hours. (% of control). * - statistically significant differences from the action of glutamate (p < 0.05, T-test). ± - No effect.
Type of culture, time of cultivation before incubation |
Incubation with test substances (preliminary, with 100 μM glutamate and subsequent) |
||
glutamate, 100 μM |
МК-801, 100 μM |
blueberry extract, 10 μg/ml |
|
1. Cereal cells -cerebellum, 11 days |
38±6 |
66±8* |
58±8* |
2. Cortex neurons, 13 days |
21±7 |
93±9* |
49±6* |
3. Cortex neurons, 14 days |
± |
± |
± |