Table 1. The results of the OSPL-502 concentration determination in plasma samples taken at appropriate time intervals, with oral (i/p) and intravenous administration (i/v) of the dosage form (mg/kg) in terms of the substance.

Time, h

Concentration of OSPL-502, ng/ml

10, i/p

2, i/v

0,25

1992,43 ± 607.54

2740,22 ± 694,15

0,5

1229,68 ± 18,78

185,65 ± 40,29

0,75

1388,14 ± 74,27

161,16 ± 35,94

1

822,21 ± 53,82

132,43 ± 20,33

1,5

2451,71 ± 256,32

103,24 ± 26,12

2

1741,54 ± 247,44

33,34 ± 17,85

4

726, 22 ± 117,72

7,24 ± 3,14

8

676,77 ± 145,23

4,22 ± 2,31

16

377,89 ± 7,87

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24

312,24 ± 25,34

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