Figure 6. Thermodynamic parameters of low-weight compounds interaction with CYP51A1. 1 – lanosterol, 2 – ketoconazole, 3 – holothurin A, 4 – asterosaponin P1, 5 – betulafolientriol, 6 – theasaponin, 7 – levisculoside G, 8 – henricioside Н1, 9 – digitonin; ΔG – change of Gibbs free energy, ΔH – change of enthalpy, -TΔS – change of entropy.