Table 1. The concentration of 5-FU in tumor tissues, µg/ml
|
Sample zones in the tumor * |
Introduction of 5-FU using a hydrogel composition Colegel |
The introduction of 5-FU orally in the form of the drug Xeloda |
Infusion 5-FU |
|||
|
1 |
0 |
0 |
0 |
0 |
0 |
0 |
|
2 |
242.0 |
82.8 |
326.5 |
0 |
0 |
0 |
|
31 |
109.0 |
234.0 |
53.6 |
157.0 |
115.0 |
104.0 |
|
32 |
56.5 |
214.0 |
172.0 |
59.0 |
256.0 |
174.0 |
|
33 |
93.0 |
214.0 |
124.3 |
134.0 |
- |
221.0 |
|
34 |
72.9 |
- |
- |
149.0 |
101.5 |
- |
|
41 |
22.3 |
155.5 |
76.7 |
18.0 |
198.0 |
228.0 |
|
42 |
0 |
145.6 |
- |
60.8 |
168.8 |
260.0 |
|
43 |
0 |
- |
- |
0 |
232.0 |
205.0 |
|
51 |
16.0 |
165.0 |
130.0 |
192.0 |
230.0 |
207.7 |
|
52 |
58.0 |
150.8 |
78.5 |
86.0 |
221.0 |
246.3 |
|
53 |
58.0 |
101.7 |
217.0 |
43.0 |
274.5 |
350.3 |
Note.* Healthy gut 5 cm proximal to the upper edge of the tumor:
1 - Paracolytic fiber.
2 - Intestinal mucosa.
Tumor:
31-34 Tumor tissue from the periphery.
41-43 - Tumor tissue from the center.
51-53 - Tissue from the surface of the tumor