Тable 1. Inhibition of rat liver mitochondrial MAO A activity (%) assayed after incubation with 5 µM pirlindole at 4ºC or 37ºC and subsequent mitochondrial wash.
|
Temperature |
Incubation time, min |
|
|
|
30 |
60 |
|
4ºC |
52+7 |
59+7 |
|
37ºC |
55+6 |
55+6 |
Note. Data represent percent of MAO A inhibition (mean + SEM; n = 7) after sedimentation of the mitochondrial pellet from the incubation mixture. Details are given in the Materials and Methods section.