Тable 2. Inhibition of rat liver mitochondrial MAO A activity assayed after incubation with 2 µM pargyline at 4ºC or 37ºC and subsequent mitochondrial wash
|
Temperature |
Incubation time, min |
||||
|
|
0 |
15 |
30 |
45 |
60 |
|
4ºC |
0 |
13+5 |
9+5 |
21+4 |
20+4 |
|
37ºC |
0 |
39+5* |
42+9* |
47+6* |
44+4* |
Note. Data represent percent of MAO A inhibition (mean + SEM; n = 7) after sedimentation of the mitochondrial pellet from the incubation mixture. Details are given in the Materials and Methods section. The asterisk shows statistically significant difference between MAO A inhibition assayed at 4ºC or 37ºC (p < 0.01).