Biobject

Type of modification

Electrochemical method

Working concentrations

Cytochrome Р450 17А1

Р450 2В4

Р450 1А2

Р45051в1

Р450 3А4

SPE/DDAB/Au _chloroform

SPE/DDAB/_chloroform SPE/MWCNT_chloroform

CV, SWV, DPV

protein film voltammetry

Substrates (1-100 µМ),

Pregnenolone

Progesterone

Diclofenac

Erythromycin

Testosterone Benzphetamine

Lanosteron

dsDNA

SPE/PIL/MWCNT

DPV

5 ÷ 500 µg/ml (guanine oxidation (G), Е=+0.60±0.01 V

0.5 ÷ 50 µg/ml (adenine oxidation (A), Е=+0.85±0.01 V

Myoglobin (Mb)

SPE/MWCNT/PB₂₉₀-b-PDMAEMA₂₄₀

CV, SWV

protein film voltammetry

10-1780 ng/ml (0.56 nM-100 nM)

Troponin I (TnI)

Myoglobin

(Mb)

Fatty acid binding protein

(H-FABP)

SPE/Au_el/DDAB

SPE/Ag_ch/DDAB

SPE/Au_el/DDAB

Stripping voltammetry

0.1-32 ng/ml (4.25 nM -1.34 nM)

1.8-32 ng/ml (76 pM -1.34 nM)

10 ng/ml (0.6 nM)

0.5 ng/ml (33 pM)

Proteins, peptides without prosthetic groups

SPE/MWCNT_chloroform

CV, SWV, DPV

diffusion controlled process

Tyrosine: 1 nM-0.1mM

0.025-1mM (in human serum)

Cytochrome P450 2B4

SPE/PbNW/AuNP/DDAB

CV, SWV

protein film voltammetry

Benzphetamine

Cytochrome с

SPE/MWCNT/PnBA₁₀₀-b-PAA₁₄₀

CV, DPV

protein film voltammetry

1-100 µM