Таблица 1. Влияние тритерпеноидов на репликацию коронавирусов по отношению к клеточным культурам

Compound ID

EC50 μM

CC50 μM

References

1

370

not tested

[18,24]

1

365 ± 12

>24000

[29]

2

not observed

20 ± 5

[29]

3

5 ± 3

15 ± 3

[29]

4

40 ± 13

>3000

[29]

5

35 ± 7

1462 ± 50

[29]

6

139 ± 20

215 ± 18

[29]

7

8 ± 2

44 ± 6

[29]

8

50 ± 10

250 ± 19

[29]

9

16 ± 1

66 ± 8

[29]

10

10

not tested

[31]

Saponans

20

not tested

[31]

11

1.7 ± 0.1

383.2 ± 0.2

[7]

Saikosaponin A

8.6 ± 0.3

228.1 ± 3.8

[7]

Saikosaponin C

19.9 ± 0.1

121.5 ± 0.1

[7]

Saikosaponin D

13.2 ± 0.3

176.2 ± 0.2

[7]

15

0.36

112

[36]

19

0.06 ± 0.02

0.81 ± 0.07

[43,44]

20

0.91 ± 0.07

7.23 ± 0.87

[43,44]

21

0.28 ± 0.09

12.47 ± 0.97

[43,44]

22

0.28 ± 0.11

9.32 ± 1.19

[43,44]

23

2.90 ± 0.25

27.29 ± 5.63

[43,44]

24

0.93 ± 0.22

13.72 ± 1.35

[43,44]