Table 2. Quantitative parameters of triterpenoids inhibiting the enzymatic activity of SARS-CoV 3CL protease
|
Compound ID |
IC50 μM |
Kia μM |
References |
|
16,17 |
10 |
8.2 ± 0.7 |
[18,36] |
|
25 |
10.3 ± 0.2 |
4.2 ± 0.6 |
[45] |
|
26 |
21.7 ± 0.19 |
not tested |
[45] |
|
27 |
2.6 ± 0.3 |
0.8 ± 0.2 |
[45] |
|
28 |
9.9 ± 0.1 |
4.0 ± 0.1 |
[45] |
|
29 |
5.5 ± 0.7 |
3.1 ± 0.0 |
[45] |