Table 3. Dark and photo induced toxicity of conjugates 1 and 5 in LNCaP and PC-3 cells
|
Conjugate |
LNCaP cells |
PC-3 cells |
||||
|
Dark toxicity (IC50, mM) |
Photo induced toxicity (IC50, mM) |
Dark IC50 / Photo IC50 ratio |
Dark toxicity (IC50, mM) |
Photo induced toxicity (IC50, mM) |
Dark IC50 / Photo IC50 ratio |
|
|
1 |
24.2 |
5.4 |
4.5 |
16.0 |
1.4 |
11.4 |
|
5 |
24.0 |
2.6 |
9.2 |
17.4 |
1.6 |
10.9 |