Table 1. Initial pharmacophore models.

Pharmacophore

Based on compounds

Number of features

HB-donors

HB-acceptors

Aromatic

Hydrophobic

1

1-6

6

6

5

-

2

7-11

4

4

6

1

3

12-14

6

5

4

-

4

15-17

5

7

2

-