Table 1. Initial pharmacophore models.
Pharmacophore |
Based on compounds |
Number of features |
|||
HB-donors |
HB-acceptors |
Aromatic |
Hydrophobic |
||
1 |
1-6 |
6 |
6 |
5 |
- |
2 |
7-11 |
4 |
4 |
6 |
1 |
3 |
12-14 |
6 |
5 |
4 |
- |
4 |
15-17 |
5 |
7 |
2 |
- |