Table 4. Oral bioavailability (Lipinski’s rules) of selected compounds.
|
Compound number |
Mol. Mass(Da) |
LogP |
HB-donors |
HB-acceptors |
Rotatable bonds |
|
19 (ZINC20530423) |
514.5 |
4.169 |
1 |
9 |
4 |
|
21 (ZINC11296605) |
420.476 |
4.841 |
2 |
7 |
7 |