Table 1. Sequences of designed knottins. Modifications in KITs in comparison to MCOTI-II are in Italic
|
Name |
Sequences |
|
MCOTI-II |
SGSDGGVCPKILKKCRRDSDCPGACICRGNGYCG |
|
KIT-1 |
- - - DGGLCYLELKKCRRDSDCEGICICRGNGYCG |
|
KIT-2 |
- - - DGVLCYLELKKCRRDSDCEGICICRGNGYCG |
|
KIT-3 |
- - - DGVKCYLELKKCRRDSDCEGICICRGNGYCG |
|
KIT-4 |
- - - DGVTCYLELKKCRRDSDCEGICICRGNGYCG |
|
KIT-5 |
- - - - GGLCYLELKKCRRDSDCEGICICRGNGYCG |
|
KIT-2_D-Leu12 |
- - - DGVLCYLELKKCRRDSDCEGICICRGNGYCG |
|
KIT-2_D-Lys13 |
- - - DGVLCYLELKKCRRDSDCEGICICRGNGYCG |
|
KIT-2_D-Lys14 |
- - - DGVLCYLELKKCRRDSDCEGICICRGNGYCG |