Table 2. Distribution of 8-OHdG concentration depending on the stage of the disease (St), the level of cell differentiation (G) and the index of proliferative activity Ki-67Ki-67

 

HER2(+), n=44

р-value

HER2(-), n=44

ТНРМЖ, n=22

Stage

St 1-2

n=25

286.7 [222.2; 746.2]

0.0498

n=20

200.2 [162.6; 562.3]

n=10

193.0 [140.4; 429.2]

St 3-4

n=19

559.2 [236.8; 1008.7]

0.0164

n=24

164.7 [122.2; 237.9]

n=12

266.4 [111.9; 1136.6]

Degree of differentiation

GI+II

n=16

477.7 [156.3; 746.2]

0.0217

n=20

168.8 [130.4; 321.7]

n=1

222.1

GIII

n=25

302.4 [223.8; 1454.5]

0.0224

n=24

194.3 [154.6; 1012.0]

n=21

258.4 [163.8; 444.6]

Proliferative activity index

Ki-67 low

n=7

691.4 [156.3; 1226.6]

-

n=16

208.1 [133.0; 431.7]

n=5

346.5 [222.2; 470.8]

Ki-67 high

n=37

393.3 [223.0; 768.5]

0.0138

n=28

162.6 [140.7; 266.4]

n=17

250.4 [116.0; 424.6]