Table 1. Estimation of the survival of mice within 120 hours after poisoning with paracetamol at a dose of 425 mg/kg.

Parameters

Groups

Intact group

Control, Paracetamol, 425 mg/kg

Xymedon, mg/kg

Xymedon conjugate with L‑ascorbic acid, мг/кг

1

10

100

200

2.1

21

210

420

Died

0

5

5

3

5

5

5

4

3

0

Survived

10

5

5

7

5

5

5

6

7

10

% survivors

100

50

50

70

50

50

50

60

70

100

Average time of death, hours

–

2.7 ± 0.2

10.3 ± 4.3*

38.5 ± 5.5*

32 ± 5.1*

21 ± 5.4*

27.3 ± 8*

37 ± 6.4*

48 ± 0*

–

* – differences with the control group are significant, at p ≤ 0.05.