Соединение*
IC50, мкМ
M-HeLa
A-375
Du-145
HepG2
MCF-7
SK-OV-3
PANC-1
HuTu 80
А549
T 98G
HL-60
Chang liver**
RPMI 1788
PP1 R = CH3
70 ± 6.3
16.1±1.5
24.6±1.9
20.7±1.5
30.6±3.2
16.7±1.9
22.4 ± 2.1
24.9±2.1
>100
20.7±2.1
26.8±3.6
28.5± 2.1
27.7±5.1
PP2 R = C2H5
80 ± 6.9
23.7±2.2
23.3±2.1
13.1±2.1
28.2±2.7
53.5±12.1
19.7 ± 1.9
23.9±2.1
>100
28.1±2.3
57.8±6.9
28.1± 1.9
15.8±1.3
PP3 R = C3H7
40 ± 3.5
47.5±5.5
33±2.8
11.7±1.6
24.9±2.5
10.3±2.5
25.0± 2.1
22.3±2.0
>100
20.2±1.8
27.5±2.1
14.1± 1.3
31.4±2.5
PP4 R = C4H9
40 ± 3.9
12.8±1.1
23±2.2
12.8±0.3
15.3±1.6
6.0±1.1
19.4 ± 1.5
6.3±0.5
43.5±4.1
11.7±1.0
21.4±1.5
21.9 ± 2.0
22.2±1.2
PP5 R = C5H11
6.5 ± 0.6
6.8±0.7
14±1.9
9.3±3.6
6.3±0.5
5.2±1.3
19.3± 1.6
6.7±0.6
42.0±4.1
19.2±1.7
20.7±3.3
14.1 ± 1.3
7.7±0.5
PP6 R = C6H13
6.1 ± 0.6
9.2±0.8
11.8±1.5
11±2.5
5.6±0.7
5.4±0.8
19.3 ± 1.9
6.5±0.6
34.2±3.0
28.6±2.5
16.8±6.5
14.8 ± 1.4
12.6±2.1
РР7 R = C7H15
4.6 ± 0.4
7.7±.0.8
10.6±2.1
13.1±5.5
4.9±0.5
5.4±0.9
16.6 ± 1.5
4.5±0.3
17.6±1.5
21.2±1.9
13.8±0.9
20.2 ± 1.7
12.1±0.9
РР8 R = C8H17
6.4 ± 0.5
6.7±1.7
12.3±1.1
3.9±3.3
3.8±0.5
5.8±0.5
15.7 ± 1.3
10.8±0.9
36.8±3.5
26.5±2.3
14.9±1.3
31.8 ± 3.0
25.1±10.6
Доксорубицин
3.0±0.3
1.3±0.1
0.9±0.1
3.3±0.2
3.1±1.6
0.5±0.1
3.2±0.2
3.0±0.2
3.0±0.2
5.7±0.5
1.7±1.89
3.0±0.3
3.3±0.37