The selectivity index of the cytotoxic action of the studied compounds, calculated relative to the IC50 for Chang liver (1) and RPMI-1788 (2) cells. 

Compounds

M-HeLa

A-375

Du-145

HepG2

MCF-7

SK-OV-3

PANC-1

HuTu 80

А549

T 98G

HL-60

Cells

1

2

1

2

1

2

1

2

1

2

1

2

1

2

1

2

1

2

1

2

1

2

PP1

0.4

0.4

1.8

1.7

1.2

1.1

1.4

1.3

0.9

0.9

1.7

1.7

1.3

1.2

1.1

1.1

-

-

1.4

1.3

1.1

1

PP2

0.4

0.2

1.2

0.7

1.2

0.7

2.1

1.2

1

0.6

0.5

0.3

1.4

0.8

1.2

0.7

-

-

1

0.6

0.5

0.3

PP3

0.4

0.8

0.3

0.7

0.4

1

1.2

2.7

0.6

1.3

1.4

3

0.6

1.3

0.6

1.4

-

-

0.7

1.6

0.5

1.1

PP4

0.6

0.6

1.7

1.7

1

1

1.7

1.7

1.4

1.5

3.7

3.7

1.1

1.1

3.5

3.5

0.5

0.5

1.9

1.9

1

1

PP5

2.2

1.2

2.1

1.1

1

0.5

1.5

0.8

2.2

1.2

2.7

1.5

0.7

0.4

2.1

1.1

0.3

0.2

0.7

0.4

0.7

0.4

PP6

2.4

2.1

1.6

1.4

1.3

1.1

1.3

1.1

2.6

2.2

2.7

2.3

0.8

0.7

2.3

1.9

0.4

0.4

0.5

0.4

0.9

0.7

РР7

4.4

2.6

2.6

1.6

1.9

1.1

1.5

0.9

4.1

2.5

3.7

2.2

1.2

0.7

4.5

2.7

1.1

0.7

0.9

0.6

1.5

0.9

РР8

5

3.9

4.6

3.6

2.6

2

8.1

6.4

8.4

6.6

5.5

4.3

2

1.6

2.9

2.3

0.9

0.7

1.2

0.9

2.1

1.7

Доксорубицин

1

1.1

2.3

2.1

3.4

2.5

0.9

3.7

1

1

6

1

0.9

6.5

1

1

1

1.1

0.5

1.1

1.8

0.6