Table 1. Standard biochemical parameters in blood plasma and urine in patients with acute pyelonephritis in different trimesters of pregnancy before and after treatment (M±m)
Indicators |
Units of measurement |
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
Healthy |
Acute pyelonephritis |
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Not pregnant |
1st trimester |
2nd trimester |
3 trimester |
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before treatment
|
basic treatment |
before treatment
|
basic treatment |
before treatment
|
basic treatment |
basic treatment + viferon |
before treatment
|
basic treatment |
basic treatment + viferon |
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Blood plasma |
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Total protein |
g/l |
65.9±4.9 |
72.6±3.4 |
70.2±4.7 |
73.4±4.5 |
72.2±4.5 |
65.1±3 |
69.1±3.1 |
67±3.8 |
67.1±2.1 |
66.1±3.4 |
66±2.8 |
Total bilirubin |
µmol/l |
9.1±0.9 |
13.2±1.4*1 |
10.3±1.1*2 |
14.2±1.2*1 |
11.3±1.3*4 |
15.6±1.8*1 |
11.7±1.9*6 |
11.2±1.7*6 |
14.3±1.4*1 |
13.3±1.1*1 |
10.3±1.2*9 |
Direct bilirubin |
µmol/l |
3.1±0.6 |
5.2±0.4*1 |
4.0±0.6*2 |
7.2±1.4*1 |
4.2±0.9*4 |
5.3±0.3*1 |
4.2±0.6*6 |
4.1±0.5*6 |
6.3±0.9*1 |
6.0±0.5*1 |
4.1±0.6*9 |
Indirect bilirubin |
µmol/l |
6.0±0.7 |
8.0±1.7 |
6.3±1.1 |
7.0±1.7 |
7.1±1.5 |
10.3±1.5*1 |
7.5±1.2*6 |
7.1±1.0*6 |
8.0±1.1*1 |
7.3±0.7 |
6.2±0.8*9 |
Urea |
mmol/l |
4.1±0.8 |
4.2±0.3 |
4.8±0.5 |
5.3±1.1 |
5.8±1.8 |
5.5±1.4 |
5.3±1.8 |
5.2±0.9 |
6.5±1.2*1 |
5.3±0.4 |
3.6±0.2*9 |
Creatinine |
µmol/l |
75.0±5.5 |
87.1±5.1*1 |
76.7±4.5*2 |
89.2±5.1*1 |
79.7±4.5*4 |
90.3±5.3*1 |
80.2±7.1 |
84.1±7.3 |
95±9.2*1 |
82.9±8.1 |
85.1±7.3 |
Urine |
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Cystatin |
mg/l |
0.18±0.02 |
0.29±0.03*1 |
0.2±0.02*2 |
0.32±0.04*1 |
0.19±0.04*4 |
0.37±0.04*1 |
0.27±0.03*1,6 |
0.23±0.05*6 |
0.4±0.07*1 |
0.29±0.03*1,9 |
0.27±0.04*1,9 |
Microalbumin |
mg/l |
17.3±2.3 |
38.5±4.7*1 |
21.8±4.2*2 |
40.1±5.1*1 |
29.5±6.1*1,4 |
43.8±6.1*1 |
33.3±7.2*1,6 |
23.0±4.4*6 |
45.8±6.3*1 |
34.8±8.2*1,9 |
35.6±5.3*1,9 |
Protein |
g/l |
0.02±0.01 |
0.03±0.01 |
0.04±0.02 |
0.03±0.03 |
0.03±0.01 |
0.04±0.01 |
0.03±0.03 |
0.03±0.01 |
0.05±0.01 |
0.03±0.03 |
0.03±0.02 |
Note. In this and in tables 2 and 3, reliable differences M (p < 0.05) are marked with an asterisk; the numbers next to the asterisk indicate in relation to the indicators of which group these differences are given.