Table 1. Standard biochemical parameters in blood plasma and urine in patients with acute pyelonephritis in different trimesters of pregnancy before and after treatment (M±m)

Indicators

Units of measurement

1

2

3

4

5

6

7

8

9

10

11

Healthy

Acute pyelonephritis

Not pregnant

1st trimester

2nd trimester

3 trimester

before treatment

 

basic

treatment

before treatment

 

basic

treatment

before treatment

 

basic

treatment

basic treatment + viferon

before treatment

 

basic

treatment

basic treatment + viferon

Blood plasma

Total protein

g/l

65.9±4.9

72.6±3.4

70.2±4.7

73.4±4.5

72.2±4.5

65.1±3

69.1±3.1

67±3.8

67.1±2.1

66.1±3.4

66±2.8

Total bilirubin

µmol/l

9.1±0.9

13.2±1.4*1

10.3±1.1*2

14.2±1.2*1

11.3±1.3*4

15.6±1.8*1

11.7±1.9*6

11.2±1.7*6

14.3±1.4*1

13.3±1.1*1

10.3±1.2*9

Direct bilirubin

µmol/l

3.1±0.6

5.2±0.4*1

4.0±0.6*2

7.2±1.4*1

4.2±0.9*4

5.3±0.3*1

4.2±0.6*6

4.1±0.5*6

6.3±0.9*1

6.0±0.5*1

4.1±0.6*9

Indirect bilirubin

µmol/l

6.0±0.7

8.0±1.7

6.3±1.1

7.0±1.7

7.1±1.5

10.3±1.5*1

7.5±1.2*6

7.1±1.0*6

8.0±1.1*1

7.3±0.7

6.2±0.8*9

Urea

mmol/l

4.1±0.8

4.2±0.3

4.8±0.5

5.3±1.1

5.8±1.8

5.5±1.4

5.3±1.8

5.2±0.9

6.5±1.2*1

5.3±0.4

3.6±0.2*9

Creatinine

µmol/l

75.0±5.5

87.1±5.1*1

76.7±4.5*2

89.2±5.1*1

79.7±4.5*4

90.3±5.3*1

80.2±7.1

84.1±7.3

95±9.2*1

82.9±8.1

85.1±7.3

Urine

Cystatin

mg/l

0.18±0.02

0.29±0.03*1

0.2±0.02*2

0.32±0.04*1

0.19±0.04*4

0.37±0.04*1

0.27±0.03*1,6

0.23±0.05*6

0.4±0.07*1

0.29±0.03*1,9

0.27±0.04*1,9

Microalbumin

mg/l

17.3±2.3

38.5±4.7*1

21.8±4.2*2

40.1±5.1*1

29.5±6.1*1,4

43.8±6.1*1

33.3±7.2*1,6

23.0±4.4*6

45.8±6.3*1

34.8±8.2*1,9

35.6±5.3*1,9

Protein

g/l

0.02±0.01

0.03±0.01

0.04±0.02

0.03±0.03

0.03±0.01

0.04±0.01

0.03±0.03

0.03±0.01

0.05±0.01

0.03±0.03

0.03±0.02

 

Note.  In this and in tables 2 and 3, reliable differences M (p < 0.05) are marked with an asterisk; the numbers next to the asterisk indicate in relation to the indicators of which group these differences are given.