Indicators

1

2

3

4

5

6

7

8

9

10

Healthy

non-pregnant

n=20

Non-pregnant women with acute pyelonephritis

n=20

Pregnant women with acute pyelonephritis

1st trimester

2nd trimester

3 trimester

before treatment

basic

treatment

before treatment

basic

treatment

basic

treatment +

Viferon

n=15

before treatment

basic

treatment

basic

treatment +

Viferon=15

n=15

n=15

n=15

malondialdehyde, µmol/l

0.26±0.01

1.5±0.1^*1

2.0±0.2^*1,2

0.84±0.03^*1,3

2.9±0.3^*1-3

1.7±0.05^*1,5

0.8±0.05^*1,5,6

2.8±0.2^*1-3

1.3±0.05^*1,8

0.7±0.06^*1,8,9

acylhydroperoxide, conventional units

0.12±0.01

0.27±0.02^*1

0.36±0.03^*1,2

0.15±0.02^*3

0.47±0.02^*1-3

0.32±0.01^*1,5 

0.1±0.01^*5,6

0.51±0.03^*1-3

0.22±0.03^*1,8

0.2±0.02^*1,8

superoxide dismutase, conventional units.

16.1±1.1

15.8±1.2

21.2±1.1^*1,2

23.4±1.9^*1

23.8±1.2^*1,2

22.9±1.3^*1

21.2±2.1^*1

24.7±1.3^*1,2

19.3±1.5^*1,8

20.1±1.3^*1,8

Catalase, U/mL

0.69±0.01

0.92±0.02^*1

0.95±0.024^*1

0.99±0.072^*1

1.13±0.02^*1-3

1±0.072^*1

0.97±0.07^*1

1.1±0.072^*1-3

1.25±0.09^*1

0.86±0.054^*1,8,9

General antioxidant activity, %

40.2±2.4

35.1±2.1^*1

34.4±1.3^*1

39.2±2.1^*3

30.7±1.7^*1-3

41.1±3.1^*5

40.2±3.5^*5

28.4±2.5^*1-3

39.2±3.5^*8

39.6±2.9^*8

Neopterin, nmol/l

4.5±0.4

5.3±0.2^*1

7.1±0.3^*1,2

5.0±0.3^*3

7.8±1.1^*1,2

7.3±0.9^*1

5.6±0.4^*1,5,6

6.7±0.9^*1,2

4.7±0.9^*8

4.6±0.1^*8

Ceruloplasmin, mg/dl

0.7±0.02

0.55±0.03^*1

0.51±0.04^*1

0.62±0.04^*1,3

0.41±0.04^*1-3

0.5±0.03^*1,5

0.66±0.03^*5,6

0.4±0.07^*1-3

0.53±0.02^*1,8

0.71±0.4^*8,9

Endothelin1,fmol/ml

2.4±0.07

2.2±0.1^*1

2±0.1^*1

2.3±0.05^*3

1.34±0.05^*1-3

1.6±0.1^*1,5

2.2±0.2^*5,6

1.26±0.04^*1-3

1.2±0.02^*1

2.1±0.06^*1,8,9

СМ_NO, µmol/l

0.76±0.05

1.4±0.2^*1

1.8±0.1^*1,2

0.95±0.04^*1,3

2.9±0.12^*1,2

2.2±0.1^*1,5

1.1±0.2^*1,5,6

3.1±0.4^*1-3

1.9±0.05^*1,8

1.1±0.07^*1,8,9

C reactive protein mg/ml

3.1±0.2

19.5±1.9^*1

23.1±1.6^*1,2

10.1±2.2^*1,3

32.1±2.4^*1-3

15.4±1.1^*1,5

8.7±0.9^*1,5,6

35.7±4.5^*1-3

12.6±0.7^*1,8

6.7±0.3^*1,8,9