Table 3. Indicators of the oxidant-antioxidant system in urine in patients with acute pyelonephritis in different trimesters of pregnancy before and after treatment (M±m)

Indicators

1

2

3

4

5

6

7

8

9

10

Healthy non-pregnant n=20

Non-pregnant women with acute pyelonephritis n=20

Pregnant women with acute pyelonephritis

1st trimester

2nd trimester

3 trimester

before treatment

basic treatment

before treatment

basic treatment

basic treatment + Viferon n=15

before treatment

basic treatment

basic treatment + Viferon n=15

n=15  

n=15

 

n=15

 

malondialdehyde, µmol/l

0.3±0.02

0.5±0.03*1

0.67±0.04*1,2

0.45±0.03*1,3

1.9±0.1*1,2

0.86±0.08*1,5

0.64±0.04*1,5,6

2.1±0.2*1-3

0.72±0.08*1,,8

0.49±0.04*1,8,9

acylhydroperoxide, conventional units

0.12±0.01

0.22±0.02*1

0.29±0.02*1,2

0.14±0.02*3

1.1±0.04*1,2

0.47±0.02*1,5

0.24±0.01*1,5,6

0.97±0.06*1-3

0.29±0.03*1,8

0.14±0.02*8,9

superoxide dismutase, conventional units

3.4±0.3

7.4±0.2*1

7.9±0.3*1

8.8±0.4*1,3

9.0±0.8*1-3

6.6±0.3*1,5

6.5±0.2*1,5

9.9±1.2*1-3

10.6±0.7*1

15.4±1.4*1,8,9

Catalase, U/mL

0.49±0.05

0.74±0.08*1

0.85±0.07*1

0.79±0.08*1

0.8±0.08*1

0.71±0.048*1

0.73±0.048*1

0.85±0.07*1

0.82±0.01*1

0.89±0.02*1

Neopterin, nmol/l

2.1±0.2

3.2±0.2*1

3.9±0.2*1,2

2.6±0.1*1,3

4.3±0.1*1-3

3.7±0.08*1,5

2.3±0.12*5,6

4.6±0.2*1-3

2±0.08*8

 1.9±0.1*8

СМNO, mmol/l

0.28±0.02

1.2±0.1*1

1.5±0.07*1,2

0.89±0.08*1,3

2.4±0.2*1-3

1.4±0.1*1,5

0.72±0.02*1,5,6

2.1±0.1*1-3

1.6±0.2*1,8

0.9±0.02*1,8,9