Biomedical Chemistry: Research and Methods, 2018, 1(3), e00036
The 40th Anniversary of the Institute of Physiologically Active Compounds of the Russian Academy of Sciences

Fluorinated α-aminoalkylphosphoryl Compounds. Synthesis, Chemical Properties and Biological Activitiy

A.Yu. Aksinenko*, V.B. Sokolov

Institute of Physiologically Active Compounds of the Russian Academy of Sciences, 1 Severny proezd, Moscow region, Chernogolovka, 142432 Russia;*e-mail: alaks@ipac.ac.ru

Key words: α-aminophosphonates; imines of polyfluoroketones; diazaphospholes; phosphorans; cyanoguanidine; biological activitiy

DOI: 10.18097/BMCRM00036

The whole version of this paper is available in Russian.

The review reports data on the synthesis of fluorine-containing α-aminophosphonates based on available organophosphorus and fluoroorganic compounds, some of their chemical properties and biological activity.

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Table 1. The inhibitory activity of fluorine-containing α-aminoalkyl phosphoryl compounds.

ACKNOWLEDGEMENTS

This research was performed within the framework the government task of 2018 (Theme No. 0090-2017-0023).

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