Эволюция методик оценки моторной функции лабораторных грызунов, моделирующих нейродегенеративные заболевания

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М.М. Чичёва
Е.В. Вихарева
А.В. Мальцев
А.А. Устюгов

Аннотация

В данной статье речь пойдёт о различных методиках оценки походки лабораторных грызунов. Данные методики являются репрезентативными для описания динамики нейродегенеративных заболеваний в рамках поведенческого тестирования на животных моделях. В статье перечислены такие методики как техника чернильных следов, беговые дорожки, а также современные системы TreadScan и CatWalk, позволяющие оценивать множество параметров походки животных. Для каждой из методик дано подробное описание и примеры её использования для оценки параметров походки при нейродегенеративных заболеваниях.

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Как цитировать
Чичёва M., Вихарева E., Мальцев A., & Устюгов A. (2018). Эволюция методик оценки моторной функции лабораторных грызунов, моделирующих нейродегенеративные заболевания. Biomedical Chemistry: Research and Methods, 1(3), e00030. https://doi.org/10.18097/BMCRM00030
Раздел
ОБЗОРЫ

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