Vol. 1 No. 3 (2018) | Biomedical Chemistry: Research and Methods

A.A. Ustyugov, M.M. Chicheva, E.A. Lysikova, E.A. Vikhareva, N.A. Sipyagina, A.N. Malkova, E.A. Straumal, E.V. Bovina, F.S. Senatov, A.I. Salimon, A.V. Maksimkin, S.A. Lermontov

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Binary Classification of Blood-Brain Barrier Penetration by the Logistic Regression Method

O.A. Raevsky, D.E. Polianczyk, O.E. Raevskaja

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The HYBOT 3D MF Application and it Integration with CoMFA

V.S. Skvortsov, A.V. Mikurova, O.A. Raevsky

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MOLTRA-II. New Three Dimensional Descriptors of the Hydrogen Bond

S.V. Trepalin, A.V. Yarkov, O.A. Raevsky

e00069

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REVIEWS

Synthesis of Water-Soluble Phthalocyanines and Modification of their Peripheral Fragments as a Method of Directed Changes in Lipophilic-Hydrophilic Properties

Hydrogen Bond Contribution to Drug Bioavailability: Cheminformatics Approach

Current Trends in the Development of Drugs for the Treatment of Alzheimer’s Disease and their Clinical Trials

Influence of Metal Ions on Microtubules as a Possible Mechanism of Pathogenesis of Alzheimer′s Disease

Evolution of Methods for Assessing the Motor Function of Laboratory Rodents - Neurodegenerative Diseases Models

Mitochondria are an Important Target in the Search for new Drugs for the Treatment of Alzheimer′s Disease and Senile Dementia

Carbamoylimines of Methyltrifluoropyruvate in the Diels-Alder’s Azareaction with Cyclopentadiene

Crown-Containing Phthalocyanines are Potential Sensibilizers for Photodynamic Therapy. Synthesis, Properties and Role of Non-Covalent Interactions

Selective Carboxylesterase Inhibitors for Improving Efficacy, Safety and Rational use of Ester-Containing Drugs

Fluorinated α-aminoalkylphosphoryl Compounds. Synthesis, Chemical Properties and Biological Activitiy

EXPERIMENTAL RESEARCH

Pharmacokinetic Studies of New Stimulator of Brain Cognitive Functions OSPL-502

The Effect of New Synthetic Analogs of Semax Peptide Preparation on AMPA-Receptors in Purkinje Neurons of Cerebellar Rats

QSAR Modeling of Acute Neurotoxicity of Some Organic Solvents with Respect to Rodents

1,5-bis[2-(dioxyphosphoryl)-4-ethylphenoxy]-3-oxapentane and its Analogs as Promising Organic Ligands for Copper(II) Binding

Luminescent Properties of Composite Systems Based on Polystyrene and Erbium(III) Phthalocyaninates in Near IR Spectral Region

Bioisosteric Analogues of Cinnamic Acid as Effective Neuroprotectors

Analysis of Immunochemical Parameters in Vertebrogenic Pain Syndrome

Calculation and Analysis of Fractal Descriptors for Protein Amino Acids in Various Conformational States

Effect of the Cycle Size and Spacer Structure in Tacrine and its Cyclopentyl Homologue Conjugates with 5-(4-trifluoromethyl-phenylamino)-1,2,4-thiadiazole on the Spectrum of their Biological Activity

SiO₂-Based Aerogels Modified by Covalently Bonded Aromatic Acids as Potential Drug Delivery Systems

QSAR Modeling of Mammal Acute Toxicity by Oral Exposure

NMR Study of the Complex Formation in Solution

Biological Activity of Alantolactones in Experiments on Cells

Properties of Calcium-Activated Chloride Currents in Rat Purkinje Cerebellum Neurons

QSAR Modeling of the NMDA Receptor Blockage by Polypharmacophoric Compounds Based on Carbazole and 1-aminoadamantane Derivatives

Effect of Endogenous Peptides on the Currents of NMDA- and AMPA-Receptors of Neurons of the Cortex, Hippocampus and Cerebellum of Rat Brain

Protective Action of the Extract of Blueberry Leaves Against Glutamate Excitotoxicity on Neurons of the Rat Cerebral Cortex

Computational Evaluation of Selectivity of Inhibition of Muscarinic Receptors M1-M4

Investigation of the Esterase Status as a Complex Biomarker of Exposure to Organophosphorus Compounds

Protective Effects of the Natural Sesquiterpene Lactones Against Damage Induced by Glutamate and Peroxide in SK-N-MC Cells

Assessment of the Adaptation Capacities of the Body Based on the Determination of the Natural Antibodies to the Endogenous Bioregulators

Development of 3D Cell Culture on Ultra-High Molecular Weight Polyethylene (UHMWPE) as the Basis of Cellular Matrix

Binary Classification of Blood-Brain Barrier Penetration by the Logistic Regression Method

PROTOCOLS OF EXPERIMENTS, USEFUL MODELS, PROGRAMS AND SERVICES

The HYBOT 3D MF Application and it Integration with CoMFA

MOLTRA-II. New Three Dimensional Descriptors of the Hydrogen Bond